Debate Statistical Analysis Plans For Observational Studies
All clinical research benefits from transparency and validity.
Debate statistical analysis plans for observational studies. Debate statistical analysis plans for observational studies bart hiemstra1 frederik keus2 jørn wetterslev3 christian gluud3 and iwan c. Transparency and validity of studies may. Debate statistical analysis plans for observational studies. Bidrag til tidsskrift tidsskriftartikel forskning peer review.
Like clinical trials recommendations for saps for observational studies increase the. Debate statistical analysis plans for observational studies. Bmc medical research methodology 19 1 233. Debate statistical analysis plans for observational studies.
We suggest to include one new item specifically applicable to observational studies to be addressed in a sap describing how adjustment for possible confounders will be handled in the. With only few amendments the guidelines for sap of a clinical trial can be. All clinical research benefits from transparency and validity. Transparency and validity of studies may increase by prospective registration of protocols and by publication of statistical analysis plans saps before data have been accessed to discern data driven analyses from pre planned analyses.